Web26 feb. 2024 · L-selectin is a 74 to 100 kDa glycoprotein involved in lymphocyte homing and adhesion to endothelial cells in peripheral lymph nodes. It contributes to leukocyte capture during the early stages... WebBackground & aims: Rye consumption has shown beneficial effects on prostate cancer tumors, as indicated by slower initial tumor growth in animal models and low
L-Selectin - an overview ScienceDirect Topics
Web31 mrt. 2015 · Due to the strong affinities of the Multi-Aptamer for L-selectin, we next explored its potential to modulate L-selectin function by inhibiting binding to endogenous ligands. One of the most well-established ligands for L-selectin is SLeX, which directly interacts with L-selectin and plays key roles in mediating initial tethering and rolling of … L-selectin, also known as CD62L, is a cell adhesion molecule found on the cell surface of leukocytes, and the blastocyst. It is coded for in the human by the SELL gene. L-selectin belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups containing a Sialyl LewisX (sLeX) … Meer weergeven The nature of the interactions between L-selectin and ligand depends on many circumstances, primarily the location of anatomically defined sites in the high vessel venules (perivascular, extravascular … Meer weergeven L-selectin is expressed constitutively on most circulating leukocytes. Over time, these molecules are released through the process of ectodomain shedding and are replaced by newly synthesized L-selectin proteins. Ectodomain shedding is largely accomplished … Meer weergeven Human immunodeficiency virus (HIV) L-selectin expressed on CD4 T lymphocytes has been implicated in mediating … Meer weergeven • L-Selectin at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • Immunology at MCG 1/physresp • Overview of all the structural information available in the Meer weergeven Lymphocytes L-selectin acts as a "homing receptor" for lymphocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present … Meer weergeven • Ryan US, Worthington RE (February 1992). "Cell-cell contact mechanisms". Current Opinion in Immunology. 4 (1): 33–37. doi:10.1016/0952-7915(92)90120-4. PMID 1375831. • Nicholson IC (2003). "CD62L (L-selectin)". Journal of Biological Regulators … Meer weergeven stephen curry with glasses
Cells Free Full-Text Selectin-Mediated Signaling&mdash ... - MDPI
WebThe integrin family of proteins consists of alpha and beta subtypes, which form transmembrane heterodimers. Integrins function as adhesion receptors for extracellular … Web1 jul. 1998 · The L-selectin adhesion molecule (CD62L) plays a primary role in mediating the initial interaction of leukocytes with vascular endothelium, a crucial step in the … Web20 dec. 2015 · My research so far has focused on cellular players in endothelial growth and regeneration, namely endothelial progenitor cells and CD31+ T-cells which act together to support endothelial cell turnover, and the maintenance of endothelial function. I have recently completed my Ph.D in Exercise Physiology at Edinburgh Napier University. stephen cyprien