Etoposide infusion reaction
WebJun 2, 2024 · Etoposide (also commonly known as VP-16) is a semisynthetic derivative of podophyllotoxin used in the treatment of certain neoplastic diseases. It is 4’-demethylepipodophyllotoxin 9- [4,6-O- (R)-ethylidene-β-D-glucopyranoside]. It is very soluble in methanol and chloroform, slightly soluble in ethanol, and sparingly soluble in … WebEtoposide is contraindicated in severe hepatic dysfunction, and it should be used with caution in patients with mild to moderate hepatic impairment. Renal impairment Since …
Etoposide infusion reaction
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WebEfficacy and Safety of Pembrolizumab Plus Investigational Agents in Combination With Chemotherapy as First-Line Treatment in Extensive-Stage Small Cell Lung Cancer (ES-SCLC) (MK-3475-B99/ KEYNOTE-B99) WebDescription Venous flare reaction, a localized allergic response associated with the administration of an irritant, is one of the most common chemotherapy infusion–related …
WebLonger infusion times may be required based on patient tolerance. Hypotension usually responds to stopping the infusion, and administration of IV fluids or other supportive … WebJun 9, 2024 · Etoposide is given by intravenous (IV, into a vein) infusion. It can also be given by mouth in the form of a capsule. The dosage and schedule is determined by the person's size, type of cancer, and mode of administration. ... Allergic Reactions: Patients can have an allergic reaction to this medication. Signs of a reaction can include: …
WebJul 25, 2024 · Etoposide side effects. Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe … WebSep 29, 2024 · Oral etoposide is not associated with hypersensitivity reactions, suggesting that the solvent may be responsible. Statements and recommendations. IgE-mediated reactions are responsible for some immediate, often severe HSRs to platinum compounds (Grade C). ... Premedication with steroids and antihistamines is effective for preventing …
WebAnaphylactic-like reactions have occurred during the initial infusion of etoposide Injection USP. Facial/tongue swelling, coughing, diaphoresis, cyanosis, tightness in throat, …
WebJun 29, 2024 · Do not administer etoposide solutions by rapid IV injection. (See Hypotension under Cautions.) Administer etoposide IV infusions over at least 30–60 minutes to minimize the risk of hypotensive reactions. If hypotensive reaction occurs, use slower rate of infusion if restarting after discontinuance and appropriate treatment. biglietti verona juventusWebJul 11, 2024 · Etoposide is a relatively well-tolerated chemotherapeutic agent.[7] Common adverse effects include alopecia and gastrointestinal toxicity. GI toxicity includes nausea, … biglietti roma - juventusWebSevere myelosuppression with resulting infection or bleeding may occur. DESCRIPTION. Etoposide (also commonly known as VP-16) is a semisynthetic derivative of … biglietti torino juventusWebAug 6, 2024 · Immediately upon initiation of the etoposide phosphate infusion, the patient experienced a severe hypersensitivity reaction and was admitted to the intensive … biglietti summit new yorkWebA flare reaction causes transient erythema along the vein proximal to the IV site that is thought to be from a local release of histamine. ... J. and others. (2024). Venous flare reactions: A case report of reactions following etoposide infusion. Clinical Journal of Oncology Nursing, 22(6), 597-599. b. Olsen, M.M., LeFebvre, K.B., Brassil, K.J ... biglietti sassuolo milan ospitiWebNov 15, 2024 · In general, etoposide may cause adverse reactions that affect the ability to drive or use machines such as fatigue, somnolence, nausea, vomiting, cortical blindness, … biglietti roma juventusWebEtoposide injection comes as a comes as a solution (liquid) or as a powder to be mixed with liquid to be slowly injected intravenously (into a vein) by a doctor or nurse in a medical … biglietti roma juventus 2023